Acne is the most common skin condition in the United States affecting most of the adolescent population. It can cause significant psychologic distress and can lead to permanent scarring. Conventional treatment of this multifactorial condition has been challenging. Many patients are now seeking natural therapies to treat their acne, and emerging evidence is giving doctors new and effective therapies which with to treat this condition. This course summarizes the naturopathic approach to treating acne from an evidence-based perspective.