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Many systemic therapies are now available for use in psoriasis and psoriatic arthritis and include the use of biologics and oral medications. This includes specific targeting of TNF and the IL-17/IL-23 pathways as well as the emergence of JAK and TYK2 inhibitors. The role of phototherapy will be discussed.
Learning Objectives:
- Participants will identify when systemic therapies are indicated for the treatment of psoriasis and how phototherapy may be included.
- Participants will compare and describe the efficacy for the use of systemic medications for psoriasis.
- Participants will discuss the evidence for the safety of JAK and TYK2 inhibitors in the context of older non-selective JAK inhibitors.
Faculty
Dr. Tina Bhutani is a board certified dermatologist who focuses on treating chronic inflammatory skin diseases including psoriasis and atopic dermatitis. She co-directs the UCSF Psoriasis and Skin Treatment Center, where she specializes in caring for patients with complex cases often requiring multiple treatment modalities including topical medications, phototherapy, systemic agents, and biologics. Dr. Bhutani believes in a well-rounded approach to care that includes considering each patient's overall wellness and mental health in addition to treating their skin disease. She believes that treating mind, body, and skin increases the probability of a successful outcome and helps patients cope with having a chronic disease.
Dr. Bhutani's research focuses on improving quality of life for patients with chronic inflammatory diseases. She seeks to further describe the mind-skin connection in order to learn how to disrupt the cycle of disease flare-up, mental stress, and worsening disease.
Editors
Dr. Hawkes is a board-certified dermatologist in the greater Sacramento area. He completed his medical school and residency at the University of Utah. During medical school, he completed a fellowship in translational immunology in the NIH-HHMI Research Scholars Program. He also received a Master’s Degree in Clinical Investigation from Rockefeller University, where he was Chief Clinical Scholar and Principal and sub-Investigator on multiple human research protocols in the Laboratory for Investigative Dermatology. He has held academic appointments in the Departments of Dermatology at the University of Utah, University of California-Davis, Icahn School of Medicine at Mount Sinai.
Dr. Hawkes is a current Councilor in the International Psoriasis Council and serves on the NPF Medical Board and Scientific Advisory Committee. He also serves as the official delegate of the AAD as a member of the international guidelines and workgroup committee for urticaria. His research has been funded by the NIH, NSF, NPF, and Dermatology Foundation, and he is the recipient of several teaching awards including NPF Outstanding Educator in Psoriatic Disease and Exceptional Teacher of the Year in the Department of Dermatology at Mount Sinai. His primary clinical and research interests include novel immune therapies for inflammatory conditions like psoriasis, atopic dermatitis, HS, alopecia areata, vitiligo, and urticaria.
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