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Dr. Kim discusses the roles of type 2 cytokines at the neuroimmune axis in PN and CSU and conveys how neuroimmune interactions give rise to chronic itch and skin lesions in each disease.
Learning Objectives:
- Understand the multifaceted actions of type 2 cytokines in mediating neuroimmune interactions
- Learn how bidirectional interactions between immune cells and neurons, including neurosensitization and neurogenic inflammation, contribute to chronic itch and inflammation in PN and CSU
Faculty
Professor, Vice Chair of Research, and Site Chair of Mount Sinai West, Icahn School of Medicine, NY, US
Brian Kim, MD, MTR, received his medical degree from the University of Washington, was a HHMI-NIH Scholar, and completed residency in dermatology at the University of Pennsylvania where he earned a Master of Translational Research (MTR). The Kim Lab focuses on mechanisms that underlie skin inflammation and the sensation of itch as a fundamental, broad, model paradigm of neuroimmunology.
He has over 150 peer-reviewed publications, multiple NIH grants, designed pivotal clinical trials that led to novel FDA-approved treatments, and is an inventor of itch-centered technologies. He holds a patent for the use of JAK inhibitors for chronic itch. He is on the editorial board for Cell Reports Medicine and the Journal of Allergy and Clinical Immunology, section editor for Journal of Immunology and on the board of reviewing editors for eLife. He is an investigator and Director of the Allen Discovery Center for Neuroimmune Interactions at Icahn School of Medicine at Mount Sinai, a Paul G. Allen Frontiers Group advised program of the Paul G. Allen Family Foundation.
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