Regenerative & Longevity Medicine in Dermatology

Science of Longevity and Measuring Biological Age

This course explores the foundational science of longevity with a focus on the measurement of biological age and its relevance to clinical practice. Participants will review key mechanisms of aging, including cellular senescence, mitochondrial dysfunction, chronic inflammation, and metabolic dysregulation, and examine validated and emerging tools used to assess biological age, such as epigenetic clocks, biomarkers of inflammation, and metabolic indices. The course emphasizes interpretation of biological age data, clinical limitations, and practical considerations for integrating longevity metrics into patient assessment, risk stratification, and preventive care strategies.

After completing this activity, participants will be able to:

• Discuss the core biologic mechanisms underlying aging and longevity, including cellular, metabolic, and inflammatory pathways.
• Differentiate chronological age from biological age and describe commonly used tools for measuring biological aging.
• Interpret biological age assessments, including epigenetic clocks and biomarker panels, within the context of clinical relevance and current evidence.
• Evaluate the strengths, limitations, and appropriate clinical use of biological age testing in preventive and longevity-focused care.
• Integrate biological age concepts into patient counseling and develop individualized strategies aimed at promoting healthy aging and disease prevention.
  

Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF), and Biologic Injectables

This session explores the role of regenerative and biologic injectables in dermatology, with a focus on platelet-based therapies including Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF), and emerging biologic injectables. Participants will review the underlying mechanisms of tissue repair, angiogenesis, and cellular signaling that support skin regeneration and longevity. The session will examine current evidence, clinical indications, preparation considerations, and safety profiles, while highlighting how these therapies integrate into comprehensive dermatologic and aesthetic treatment plans aimed at optimizing skin health, function, and long-term outcomes.

After completing this activity, participants will be able to:

• Discuss the biologic mechanisms by which PRP, PRF, and related regenerative injectables support tissue repair, collagen remodeling, and skin longevity.
• Compare and contrast PRP and PRF, including differences in preparation, composition, clinical indications, and durability of effect.
• Review the current evidence base supporting the use of platelet-based and biologic injectables in dermatologic, aesthetic, and hair-related conditions.
• Identify appropriate patient selection, safety considerations, and contraindications for regenerative injectable therapies in dermatology practice.
• Discuss how regenerative and biologic injectables can be integrated into multimodal treatment strategies for skin rejuvenation, wound healing, and longevity-focused dermatologic care
  

Epigenetics in Dermatology: Mechanisms of Skin Aging and Regeneration

This course examines the role of epigenetic regulation in skin aging and dermatologic disease. Participants will explore how epigenetic mechanisms including DNA methylation, histone modification, and non-coding RNA signaling contribute to intrinsic and extrinsic skin aging, inflammation, barrier dysfunction, and altered repair processes. The course will review how environmental exposures, lifestyle factors, and therapeutic interventions influence the cutaneous epigenome, and discuss emerging evidence for epigenetic-informed approaches to dermatologic prevention, treatment, and healthy skin aging.

After completing this activity, participants will be able to:

• Describe key epigenetic mechanisms and their role in regulating skin structure, function, and aging.
• Discuss how intrinsic aging and extrinsic factors (eg, UV exposure, pollution, nutrition, stress) influence epigenetic changes in the skin.
• Evaluate current evidence linking epigenetic modifications to dermatologic aging, inflammation, and disease susceptibility.
• Review how lifestyle, environmental, and therapeutic interventions may modulate epigenetic pathways relevant to skin health and aging.
• Utilize epigenetic concepts to dermatology practice to support personalized approaches to aging, prevention, and regenerative skin care.

Photobiomodulation: Red Light for Longevity

This session explores the role of regenerative and biologic injectables in dermatology, with a focus on platelet-based therapies including Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF), and emerging biologic injectables. Participants will review the underlying mechanisms of tissue repair, angiogenesis, and cellular signaling that support skin regeneration and longevity. The session will examine current evidence, clinical indications, preparation considerations, and safety profiles, while highlighting how these therapies integrate into comprehensive dermatologic and aesthetic treatment plans aimed at optimizing skin health, function, and long-term outcomes.
Learning Objectives: 

• Discuss the biologic mechanisms by which PRP, PRF, and related regenerative injectables support tissue repair, collagen remodeling, and skin longevity.
• Compare and contrast PRP and PRF, including differences in preparation, composition, clinical indications, and durability of effect.
• Review the current evidence base supporting the use of platelet-based and biologic injectables in dermatologic, aesthetic, and hair-related conditions.
• Identify appropriate patient selection, safety considerations, and contraindications for regenerative injectable therapies in dermatology practice.
• Discuss how regenerative and biologic injectables can be integrated into multimodal treatment strategies for skin rejuvenation, wound healing, and longevity-focused dermatologic care
  

Laser Therapy in Regenerative & Integrative Dermatology: From Tissue Repair to Rejuvenation

This course focuses exclusively on laser technologies used in regenerative dermatology and their role in tissue repair, remodeling, and skin rejuvenation. Participants will examine how different laser modalities stimulate regenerative pathways such as controlled thermal injury, collagen and elastin neosynthesis, vascular remodeling, and immune modulation. The course will review clinical evidence supporting laser use across key indications including scar revision, photodamage, dyspigmentation, inflammatory dermatoses, and hair disorders. Emphasis is placed on device selection, parameter optimization, patient selection, and safety considerations including those in skin of color to support effective, evidence-informed laser treatment planning in dermatology practice.

After completing this activity, participants will be able to:

• Describe the principles of regenerative dermatology and how laser-based therapies promote tissue repair, remodeling, and rejuvenation.
• Differentiate major laser modalities (ablative, non-ablative fractional, vascular, pigment-targeting, and hair-targeting lasers) by mechanism and regenerative effects.
• Evaluate clinical evidence supporting laser use for scarring, photoaging, dyspigmentation, inflammatory skin conditions, and hair disorders.
• Apply laser selection and parameter optimization strategies by diagnosis, skin type, and treatment goals.
• Implement laser-specific safety protocols and complication management strategies, particularly in darker skin types.

Non-CME Additional Resource:

Growth Factors, Bioactive Peptides, and Exosomes: Evidence-Informed Integration of Regenerative Principles

This course examines the role of exosomes, growth factors, and bioactive peptides as key mediators of tissue repair, regeneration, and healthy skin aging. Participants will explore how these bioactive signaling molecules influence cellular senescence, inflammation, collagen and elastin remodeling, angiogenesis, mitochondrial function, and barrier integrity, processes that are all relevant to both cutaneous regeneration and longevity. We'll review the current evidence for dermatologic applications in skin rejuvenation, hair disorders, age-related skin changes, healing, and scarring, while addressing limitations related to product variability, delivery methods, safety, and regulatory oversight. Emphasis is placed on responsible integration of regenerative biologics into dermatology practice to support both regenerative outcomes and healthy aging.

After completing this activity, participants will be able to:

• Describe the biologic roles of exosomes, growth factors, and bioactive peptides in cutaneous regeneration, aging, and longevity pathways.
• Review mechanisms of cell-to-cell communication relevant to skin repair and aging, including extracellular vesicle signaling, peptide-mediated pathways, and their effects on cellular senescence and inflammation.
• Evaluate the clinical evidence supporting regenerative and anti-aging applications of exosomes, growth factors, and peptides in dermatology, including skin rejuvenation, wound healing, scarring, and hair disorders.
• Differentiate product types, sources, and delivery considerations, including challenges related to standardization, quality control, and regulatory status in the context of longevity-focused care.
• Apply safety, ethical, and evidence-informed principles when incorporating regenerative biologics into dermatologic strategies aimed at promoting healthy skin aging and longevity.