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Our GI tract is essentially one long tube extending from our mouth to our anus, and one of its main functions is sequestering the external environment (such as food and bacteria) from our bloodstream. When these defenses fail, it can lead to intestinal permeability and have a wide range of effects on our health, including our skin. This article will review the pathophysiology and causes of intestinal permeability as well as clinical methods to test for it. It will also review published research on the association between intestinal permeability and skin conditions such as eczema, psoriasis, and dermatitis herpetiformis.
Dr. Julie Greenberg is a licensed Naturopathic Doctor (ND) and Registered Herbalist RH(AHG) who specializes in integrative dermatology. She is the founder of the Center for Integrative Dermatology, a holistic clinic that approaches skin and hair problems by finding and treating the root cause. Dr. Greenberg holds degrees from Northwestern University (BA), Stanford University (MBA) and Bastyr University (ND). Her research on the gut microbiome of acne patients has been published in a leading peer-reviewed clinical dermatology journal. While at naturopathic medical school, Dr. Greenberg received training with leading experts in dermatology at the University of Washington Medical School Dermatology Clinic and Seattle Children’s Hospital Pediatric Dermatology Clinic. She lectures at naturopathic medical schools and speaks at conferences across the U.S. on the topics of hair, skin and nails.
Dr. Raja Sivamani is a board-certified dermatologist and practices as an integrative dermatologist at Pacific Skin Institute. He is an Adjunct Associate Professor of Clinical Dermatology at the University of California, Davis and Director of Clinical Research and the Clinical Trials Unit.He is also an Adjunct Assistant Professor in the Department of Biological Sciences at the California State University, Sacramento and an Associate Professor of Dermatology at California Northstate University, College of Medicine.He engages in clinical practice as well as both clinical and translational research that integrates bioengineering, nutrition, cosmetics, and skin biology. With training in both Allopathic and Ayurvedic medicine, he takes an integrative approach to his patients and in his research.He has published over 100 peer-reviewed research manuscripts, 10 textbook chapters, and a textbook entitled Cosmeceuticals and Active Cosmetics, 3rd Edition with a passion for expanding the evidence and boundaries of integrative medicine for skin care.